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Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma?

BACKGROUND: RRM1 and ERCC1 overexpression has been extensively investigated as potential predictive markers of tumor sensitivity to conventional chemotherapy agents, most thoroughly in lung cancer. However, data in pancreatic cancer are scarce. METHODS: We investigated the mRNA and protein expressio...

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Bibliografski detalji
Glavni autori: Valsecchi, Matias E, Holdbrook, Thomas, Leiby, Benjamin E, Pequignot, Edward, Littman, Susan J, Yeo, Charles J, Brody, Jonathan R, Witkiewicz, Agnieszka K
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364898/
https://ncbi.nlm.nih.gov/pubmed/22436573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-104
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