INDUCTION OF MONOCYTE CHEMOATTRACTANT PROTEIN-1 BY NICOTINE IN PANCREATIC DUCTAL ADENOCARCINOMA CELLS: ROLE OF OSTEOPONTIN

INTRODUCTION: Cigarette smoke and nicotine are among the leading environmental risk factors for developing pancreatic ductal adenocarcinoma (PDA). We showed recently that nicotine induces osteopontin (OPN), a protein that plays critical roles in inflammation and tumor metastasis. We identified an OP...

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Main Authors: Lazar, Melissa, Sullivan, Jennifer, Chipitsyna, Galina, Aziz, Tamer, Salem, Ahmed F, Gong, Qiaoke, Witkiewicz, Agnes, Denhardt, David T., Yeo, Charles J., Arafat, Hwyda A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908036/
https://ncbi.nlm.nih.gov/pubmed/20579680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2010.05.002
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