EXPRESSION OF A PRO-METASTATIC SPLICE VARIANT OF OSTEOPONTIN, OPNC, IN HUMAN PANCREATIC DUCTAL ADENOCARCINOMA

INTRODUCTION: Osteopontin (OPN) is a secreted phosphoprotein that confers on cancer cells a migratory phenotype. We showed recently that nicotine, a major risk factor in pancreatic ductal adenocarcinoma (PDA), increases OPN expression in PDA cells. An OPN splice variant, OPNc, supports anchorage ind...

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Autores principales: Sullivan, Jennifer, Blair, Laurel, Alnajar, Amer, Aziz, Tamer, Ng, Chee Yuan, Chipitsyna, Galina, Gong, Qiaoke, Witkiewicz, Agnes, Weber, Georg F., Denhardt, David T., Yeo, Charles J., Arafat, Hwyda A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777713/
https://ncbi.nlm.nih.gov/pubmed/19628079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2009.03.036
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