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Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma?

BACKGROUND: RRM1 and ERCC1 overexpression has been extensively investigated as potential predictive markers of tumor sensitivity to conventional chemotherapy agents, most thoroughly in lung cancer. However, data in pancreatic cancer are scarce. METHODS: We investigated the mRNA and protein expressio...

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Detalhes bibliográficos
Main Authors: Valsecchi, Matias E, Holdbrook, Thomas, Leiby, Benjamin E, Pequignot, Edward, Littman, Susan J, Yeo, Charles J, Brody, Jonathan R, Witkiewicz, Agnieszka K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364898/
https://ncbi.nlm.nih.gov/pubmed/22436573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-104
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