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Significance of RRM1 and ERCC1 expression in resectable pancreatic adenocarcinoma

The identification of molecular markers, useful for therapeutic decisions in pancreatic cancer patients, is crucial for advances in disease management. Gemcitabine, although a cornerstone of current therapy, has limited efficacy. RRM1 is a key molecule for gemcitabine efficacy and is also involved i...

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Detalhes bibliográficos
Main Authors: Akita, H, Zheng, Z, Takeda, Y, Kim, C, Kittaka, N, Kobayashi, S, Marubashi, S, Takemasa, I, Nagano, H, Dono, K, Nakamori, S, Monden, M, Mori, M, Doki, Y, Bepler, G
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913371/
https://ncbi.nlm.nih.gov/pubmed/19543324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.158
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