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Modulation of K(V)1.3 channels by protein kinase A I in T lymphocytes is mediated by the disc large 1-tyrosine kinase Lck complex

The cAMP/PKA signaling system constitutes an inhibitory pathway in T cells and, although its biochemistry has been thoroughly investigated, its possible effects on ion channels are still not fully understood. K(V)1.3 channels play an important role in T-cell activation, and their inhibition suppress...

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מידע ביבליוגרפי
Main Authors: Kuras, Zerrin, Kucher, Vladimir, Gordon, Scott M., Neumeier, Lisa, Chimote, Ameet A., Filipovich, Alexandra H., Conforti, Laura
פורמט: Artigo
שפה:Inglês
יצא לאור: American Physiological Society 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362003/
https://ncbi.nlm.nih.gov/pubmed/22378744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00263.2011
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