Improved stability of multivalent antibodies containing the human collagen XV trimerization domain

We recently described the in vitro and in vivo properties of an engineered homotrimeric antibody made by fusing the N-terminal trimerization region of collagen XVIII NC1 domain to the C-terminus of a scFv fragment [trimerbody (scFv-NC1)(3); 110 kDa]. Here, we demonstrated the utility of the N-termin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cuesta, Ángel M, Sánchez-Martín, David, Blanco-Toribio, Ana, Villate, Maider, Enciso-Álvarez, Kelly, Alvarez-Cienfuegos, Ana, Sainz-Pastor, Noelia, Sanz, Laura, Blanco, Francisco J, Álvarez-Vallina, Luis
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2012
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361658/
https://ncbi.nlm.nih.gov/pubmed/22453098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.4.2.19140
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