Efficient production of single-chain fragment variable-based N-terminal trimerbodies in Pichia pastoris

BACKGROUND: Recombinant antibodies are highly successful in many different pathological conditions and currently enjoy overwhelming recognition of their potential. There are a wide variety of protein expression systems available, but almost all therapeutic antibodies are produced in mammalian cell l...

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Bibliographic Details
Published in:Microb Cell Fact
Main Authors: Blanco-Toribio, Ana, Lacadena, Javier, Nuñez-Prado, Natalia, Álvarez-Cienfuegos, Ana, Villate, Maider, Compte, Marta, Sanz, Laura, Blanco, Francisco J, Álvarez-Vallina, Luis
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249718/
https://ncbi.nlm.nih.gov/pubmed/25112455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-014-0116-1
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