RNA surveillance is required for endoplasmic reticulum homeostasis

The unfolded protein response (UPR) is an intracellular stress-signaling pathway that counteracts the accumulation of misfolded proteins in the endoplasmic reticulum (ER). Because defects in ER protein folding are associated with many pathological states, including metabolic, neurologic, genetic, an...

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Bibliografiset tiedot
Päätekijät: Sakaki, Kenjiro, Yoshina, Sawako, Shen, Xiaohua, Han, Jaeseok, DeSantis, Melinda R., Xiong, Mon, Mitani, Shohei, Kaufman, Randal J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2012
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361423/
https://ncbi.nlm.nih.gov/pubmed/22562797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110589109
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