RNA surveillance is required for endoplasmic reticulum homeostasis

The unfolded protein response (UPR) is an intracellular stress-signaling pathway that counteracts the accumulation of misfolded proteins in the endoplasmic reticulum (ER). Because defects in ER protein folding are associated with many pathological states, including metabolic, neurologic, genetic, an...

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Bibliografiska uppgifter
Huvudupphovsmän: Sakaki, Kenjiro, Yoshina, Sawako, Shen, Xiaohua, Han, Jaeseok, DeSantis, Melinda R., Xiong, Mon, Mitani, Shohei, Kaufman, Randal J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2012
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361423/
https://ncbi.nlm.nih.gov/pubmed/22562797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110589109
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