RNA surveillance is required for endoplasmic reticulum homeostasis

The unfolded protein response (UPR) is an intracellular stress-signaling pathway that counteracts the accumulation of misfolded proteins in the endoplasmic reticulum (ER). Because defects in ER protein folding are associated with many pathological states, including metabolic, neurologic, genetic, an...

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Detalhes bibliográficos
Main Authors: Sakaki, Kenjiro, Yoshina, Sawako, Shen, Xiaohua, Han, Jaeseok, DeSantis, Melinda R., Xiong, Mon, Mitani, Shohei, Kaufman, Randal J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361423/
https://ncbi.nlm.nih.gov/pubmed/22562797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110589109
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