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Inositol-requiring 1/X-box-binding protein 1 is a regulatory hub that links endoplasmic reticulum homeostasis with innate immunity and metabolism

Inositol-requiring 1 (IRE1)/X-box-binding protein 1 (XBP1)-mediated signalling represents the most conserved branch of the unfolded protein response. A series of recent studies reveal novel and potentially ancient roles for this pathway in the coordination of metabolic and immune responses.

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Detalhes bibliográficos
Main Authors: Kaufman, Randal J, Cao, Siyan
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042734/
https://ncbi.nlm.nih.gov/pubmed/20533428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201000076
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