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ATP released from cardiac fibroblasts via connexin hemichannels activates profibrotic P2Y(2) receptors
Cardiac fibroblasts (CFs) play an essential role in remodeling of the cardiac extracellular matrix. Extracellular nucleotide signaling may provoke a profibrotic response in CFs. We tested the hypothesis that physical perturbations release ATP from CFs and that ATP participates in profibrotic signali...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Federation of American Societies for Experimental Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3360157/ https://ncbi.nlm.nih.gov/pubmed/22415310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-204677 |
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