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Expression of XBP1s in bone marrow stromal cells is critical for myeloma cell growth and osteoclast formation
BM stromal cells (BMSCs) are key players in the microenvironmental support of multiple myeloma (MM) cell growth and bone destruction. A spliced form of the X-box–binding protein-1 (XBP1s), a major proximal effector of unfolded protein response signaling, is highly expressed in MM cells and plays an...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3359740/ https://ncbi.nlm.nih.gov/pubmed/22427205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-353300 |
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