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Increased signaling through p62 in the marrow microenvironment increases myeloma cell growth and osteoclast formation
Adhesive interactions between multiple myeloma (MM) cells and marrow stromal cells activate multiple signaling pathways including nuclear factor κB (NF-κB), p38 mitogen-activated protein kinase (MAPK), and Jun N-terminal kinase (JNK) in stromal cells, which promote tumor growth and bone destruction....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2686139/ https://ncbi.nlm.nih.gov/pubmed/19282458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-08-173948 |
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