Expression of XBP1s in bone marrow stromal cells is critical for myeloma cell growth and osteoclast formation

BM stromal cells (BMSCs) are key players in the microenvironmental support of multiple myeloma (MM) cell growth and bone destruction. A spliced form of the X-box–binding protein-1 (XBP1s), a major proximal effector of unfolded protein response signaling, is highly expressed in MM cells and plays an...

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Detalhes bibliográficos
Main Authors: Xu, Guoshuang, Liu, Kai, Anderson, Judy, Patrene, Kenneth, Lentzsch, Suzanne, Roodman, G. David, Ouyang, Hongjiao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359740/
https://ncbi.nlm.nih.gov/pubmed/22427205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-353300
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