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Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning
Adoptive cell therapy with tumor-targeted T cells is a promising approach to cancer therapy. Enhanced clinical outcome using this approach requires conditioning regimens with total body irradiation, lymphodepleting chemotherapy, and/or additional cytokine support. However, the need for prior conditi...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3359735/ https://ncbi.nlm.nih.gov/pubmed/22354001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-400044 |
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