Carcinogenicity of benzo[a]pyrene 4,5-, 7,8-, and 9,10-oxides on mouse skin.

Benzo[a]pyrene and three arene oxides of benzo[a]pyrene (benzo[a]pyrene 4,5-, 7,8-, and 9,10-oxides) have been tested for carcinogenicity in mice by topical application of each compound (0.1 or 0.4 mumol) once every 2 weeks for 60 weeks. At the high dose, benzo[a]pyrene and the 7,8-oxide were highly...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Levin, W, Wood, A W, Yagi, H, Dansette, P M, Jerina, D M, Conney, A H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1976
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335877/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1061121/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.1.243
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