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Fungal oxidation of (+/-)-9,10-dihydroxy-9,10-dihydrobenzo[a]pyrene: formation of diastereomeric benzo[a]pyrene 9,10-diol 7,8-epoxides.

The filamentous fungus Cunninghamella elegans oxidized (+/-) trans-9,10-dihydroxy-9,10-dihydrobenzo[a]-pyrene to a complex mixture of metabolites which were detected by high-pressure liquid chromatography. Two of the metabolites were identified as (+/-)7 beta, 8 alpha, 9 alpha, 10 beta-tetrahydroxy-...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Cerniglia, C E, Gibson, D T
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1980
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349882/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933504/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.8.4554
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