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Carcinogenicity of benzo[a]pyrene 4,5-, 7,8-, and 9,10-oxides on mouse skin.

Benzo[a]pyrene and three arene oxides of benzo[a]pyrene (benzo[a]pyrene 4,5-, 7,8-, and 9,10-oxides) have been tested for carcinogenicity in mice by topical application of each compound (0.1 or 0.4 mumol) once every 2 weeks for 60 weeks. At the high dose, benzo[a]pyrene and the 7,8-oxide were highly...

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Autors principals: Levin, W, Wood, A W, Yagi, H, Dansette, P M, Jerina, D M, Conney, A H
Format: Artigo
Idioma:Inglês
Publicat: 1976
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC335877/
https://ncbi.nlm.nih.gov/pubmed/1061121
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