Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain

Genome-wide association studies have nominated many genetic variants for common human traits, including diseases, but in many cases the underlying biological reason for a trait association is unknown. Subsets of genetic polymorphisms show a statistical association with transcript expression levels,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Hernandez, Dena G., Nalls, Mike A., Moore, Matthew, Chong, Sean, Dillman, Allissa, Trabzuni, Daniah, Gibbs, J. Raphael, Ryten, Mina, Arepalli, Sampath, Weale, Michael E., Zonderman, Alan B., Troncoso, Juan, O'Brien, Richard, Walker, Robert, Smith, Colin, Bandinelli, Stefania, Traynor, Bryan J., Hardy, John, Singleton, Andrew B., Cookson, Mark R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Academic Press 2012
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358430/
https://ncbi.nlm.nih.gov/pubmed/22433082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.03.020
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