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Pharmacological Properties of Bivalent Ligands Containing Butorphan Linked to Nalbuphine, Naltrexone and Naloxone at μ, δ and κ Opioid Receptors
Investigation of bivalent ligands at μ, δ and κ opioid receptors is now focused on the preparation of ligands containing κ agonist and μ agonist/antagonist pharmacophores at one end joined by a linking chain containing the μ antagonists pharmacophores (naltrexone, naloxone or nalbuphine) at the othe...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3357624/ https://ncbi.nlm.nih.gov/pubmed/17407276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm061327z |
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