ロード中...

Effect of Linker Substitution on the Binding of Butorphan Univalent and Bivalent Ligands to Opioid Receptors

A series of bivalent hydroxy ether butorphan ligands were prepared and their binding affinities at the opioid receptors determined. Addition of a hydroxy group to a hydrocarbon chain can potentiate binding affinity up to 27 and 86 fold at the mu and kappa opioid receptors, respectively. Two bivalent...

詳細記述

保存先:
書誌詳細
主要な著者: Fulton, Brian S., Knapp, Brian L., Bidlack, Jean M., Neumeyer, John L.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834170/
https://ncbi.nlm.nih.gov/pubmed/20144870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.01.101
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!