Divergent Genomic and Epigenomic Landscapes of Lung Cancer Subtypes Underscore the Selection of Different Oncogenic Pathways during Tumor Development

For therapeutic purposes, non-small cell lung cancer (NSCLC) has traditionally been regarded as a single disease. However, recent evidence suggest that the two major subtypes of NSCLC, adenocarcinoma (AC) and squamous cell carcinoma (SqCC) respond differently to both molecular targeted and new gener...

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Autors principals: Lockwood, William W., Wilson, Ian M., Coe, Bradley P., Chari, Raj, Pikor, Larissa A., Thu, Kelsie L., Solis, Luisa M., Nunez, Maria I., Behrens, Carmen, Yee, John, English, John, Murray, Nevin, Tsao, Ming-Sound, Minna, John D., Gazdar, Adi F., Wistuba, Ignacio I., MacAulay, Calum E., Lam, Stephen, Lam, Wan L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357406/
https://ncbi.nlm.nih.gov/pubmed/22629454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037775
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