Integrative Genomic Analyses Identify BRF2 as a Novel Lineage-Specific Oncogene in Lung Squamous Cell Carcinoma

BACKGROUND: Traditionally, non-small cell lung cancer is treated as a single disease entity in terms of systemic therapy. Emerging evidence suggests the major subtypes—adenocarcinoma (AC) and squamous cell carcinoma (SqCC)—respond differently to therapy. Identification of the molecular differences b...

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Hlavní autoři: Lockwood, William W., Chari, Raj, Coe, Bradley P., Thu, Kelsie L., Garnis, Cathie, Malloff, Chad A., Campbell, Jennifer, Williams, Ariane C., Hwang, Dorothy, Zhu, Chang-Qi, Buys, Timon P. H., Yee, John, English, John C., MacAulay, Calum, Tsao, Ming-Sound, Gazdar, Adi F., Minna, John D., Lam, Stephen, Lam, Wan L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910599/
https://ncbi.nlm.nih.gov/pubmed/20668658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1000315
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