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DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers
Chromosomal translocation is the best-characterized genetic mechanism for oncogene activation. However, there are documented examples of activation by alternate mechanisms, for example gene dosage increase, though its prevalence is unclear. Here, we answered the fundamental question of the contribut...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849646/ https://ncbi.nlm.nih.gov/pubmed/18391978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.98 |
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