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Synthesis of Phidianidines A and B

Reaction of a substituted indole-3-acetyl chloride with N-5-azidopentyl-N′-hydroxyguanidine generated a substituted 3-(5-azidopentylamino)-5-((indol-3-yl)-methyl)-1,2,4-oxadiazole. Reduction of the azide with zinc and ammonium formate afforded the amine, which was elaborated to the guanidine, comple...

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Detalhes bibliográficos
Main Authors: Lin, Hong-Yu, Snider, Barry B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356445/
https://ncbi.nlm.nih.gov/pubmed/22524523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo300449n
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