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Synthesis of the Spiroiminal Moiety of Marineosins A and B

[Image: see text] A model for the spiroiminal moiety of marineosins A and B was prepared starting from methylvalerolactone. Addition of vinylmagnesium bromide, protection of the alcohol, and reaction of the vinyl ketone with a protected pyrrole-2-carbonitrile N-oxide gave an isoxazoline. Hydrogenoly...

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Hlavní autoři: Cai, Xiao-Chuan, Wu, Xiaoxing, Snider, Barry B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877921/
https://ncbi.nlm.nih.gov/pubmed/20218641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100333d
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