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Synthesis of (−)-Chaetominine
[Image: see text] The tricyclic hydroxy imidazolidinone was converted to chaetominine in seven steps in 22% overall yield. The key step was the construction of the δ-lactam by heating an amino ester with a catalytic amount of DMAP in toluene at reflux.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527753/ https://ncbi.nlm.nih.gov/pubmed/17944481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol7022483 |
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