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Synthesis of the Spiroiminal Moiety of Marineosins A and B
[Image: see text] A model for the spiroiminal moiety of marineosins A and B was prepared starting from methylvalerolactone. Addition of vinylmagnesium bromide, protection of the alcohol, and reaction of the vinyl ketone with a protected pyrrole-2-carbonitrile N-oxide gave an isoxazoline. Hydrogenoly...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877921/ https://ncbi.nlm.nih.gov/pubmed/20218641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100333d |
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