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Synthesis of the Isoxazolo[4,3,2-de]phenanthridinone Moiety of the Parnafungins
[Image: see text] A practical route to the labile tetracyclic isoxazolo[4,3,2-de]phenanthridinone moiety of the antifungal parnafungins has been developed. Zinc reduction of a methyl 2'-hydroxymethyl-2-nitro-3-biphenylcarboxylate, which was prepared by a Suzuki coupling, afforded a benzisoxazol...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760249/ https://ncbi.nlm.nih.gov/pubmed/19496595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol901054r |
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