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Synthesis of the Spiroiminal Moiety and Approaches to the Synthesis of Marineosins A and B

A short and efficient synthesis of model spiroiminals that have the same stereochemistry but different conformations than marineosins A and B was carried out in 6-7 steps from 6-methyltetrahydropyran-2-one. These spiroiminals were also prepared biomimetically by reduction of an enol ether. A more hi...

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Détails bibliographiques
Auteurs principaux: Cai, Xiao-Chuan, Snider, Barry B.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885995/
https://ncbi.nlm.nih.gov/pubmed/24199754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo402178r
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