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Mechanism of Nucleic Acid Unwinding by SARS-CoV Helicase
The non-structural protein 13 (nsp13) of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) is a helicase that separates double-stranded RNA (dsRNA) or DNA (dsDNA) with a 5′→3′ polarity, using the energy of nucleotide hydrolysis. We determined the minimal mechanism of helicase function by nsp1...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3352918/ https://ncbi.nlm.nih.gov/pubmed/22615777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036521 |
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