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Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase
The superfamily 1 helicase nonstructural protein 13 (nsp13) is required for SARS-CoV-2 replication. The mechanism and regulation of nsp13 has not been explored at the single-molecule level. Specifically, force-dependent unwinding experiments have yet to be performed for any coronavirus helicase. Her...
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| Gepubliceerd in: | Biophys J |
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| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Biophysical Society
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7837305/ https://ncbi.nlm.nih.gov/pubmed/33340543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.11.2276 |
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