Cooperative translocation enhances the unwinding of duplex DNA by SARS coronavirus helicase nsP13

SARS coronavirus encodes non-structural protein 13 (nsP13), a nucleic acid helicase/NTPase belonging to superfamily 1 helicase, which efficiently unwinds both partial-duplex RNA and DNA. In this study, unwinding of DNA substrates that had different duplex lengths and 5′-overhangs was examined under...

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Autori principali: Lee, Na-Ra, Kwon, Hyun-Mi, Park, Kkothanahreum, Oh, Sangtaek, Jeong, Yong-Joo, Kim, Dong-Eun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
Soggetti:
Nucleic Acid Enzymes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995068/
https://ncbi.nlm.nih.gov/pubmed/20671029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq647
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