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Severe Acute Respiratory Syndrome Coronavirus Replication Inhibitor That Interferes with the Nucleic Acid Unwinding of the Viral Helicase

Severe acute respiratory syndrome (SARS) is a highly contagious disease, caused by SARS coronavirus (SARS-CoV), for which there are no approved treatments. We report the discovery of a potent inhibitor of SARS-CoV that blocks replication by inhibiting the unwinding activity of the SARS-CoV helicase...

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Autori principali: Adedeji, Adeyemi O., Singh, Kamalendra, Calcaterra, Nicholas E., DeDiego, Marta L., Enjuanes, Luis, Weiss, Susan, Sarafianos, Stefan G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421890/
https://ncbi.nlm.nih.gov/pubmed/22733076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00957-12
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