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Synthesis of Purine Modified 2′-C-Methyl Nucleosides as Potential Anti-HCV Agents
Based on the anti-hepatitis C activity of 2′-C-methyl-adenosine and 2′-C-methyl-guanosine, a series of new modified purine 2′-C-methyl nucleosides was prepared as potential anti-hepatitis C virus agents. Herein, we report the synthesis of both 6-modified and 2-modified purine 2′-C-methyl-nucleosides...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3352596/ https://ncbi.nlm.nih.gov/pubmed/21983447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.09.034 |
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