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Renal phenotype of Et-1 transgenic mice is modulated by androgens

INTRODUCTION: Activation of the endothelin (ET) system promotes inflammation and fibrosis in various tissues including the kidney. Male ET-1 transgenic mice are characterized by chronic kidney inflammation and renal scarring. We hypothesized that this renal phenotype might be modulated by androgens....

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Detalhes bibliográficos
Main Authors: Kalk, P, Thöne-Reineke, C, Schwarz, A, Godes, M, Bauer, C, Pfab, T, Hocher, B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351960/
https://ncbi.nlm.nih.gov/pubmed/19258213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-783X-14-2-55
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