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Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes

While high levels of Pkd1 expression are detected in tissues of patients with autosomal dominant polycystic kidney disease (ADPKD), it is unclear whether enhanced expression could be a pathogenetic mechanism for this systemic disorder. Three transgenic mouse lines were generated from a Pkd1-BAC modi...

詳細記述

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書誌詳細
主要な著者: Kurbegovic, Almira, Côté, Olivier, Couillard, Martin, Ward, Christopher J., Harris, Peter C., Trudel, Marie
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081642/
https://ncbi.nlm.nih.gov/pubmed/20053665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp588
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