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Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes
While high levels of Pkd1 expression are detected in tissues of patients with autosomal dominant polycystic kidney disease (ADPKD), it is unclear whether enhanced expression could be a pathogenetic mechanism for this systemic disorder. Three transgenic mouse lines were generated from a Pkd1-BAC modi...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4081642/ https://ncbi.nlm.nih.gov/pubmed/20053665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp588 |
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