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Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes
While high levels of Pkd1 expression are detected in tissues of patients with autosomal dominant polycystic kidney disease (ADPKD), it is unclear whether enhanced expression could be a pathogenetic mechanism for this systemic disorder. Three transgenic mouse lines were generated from a Pkd1-BAC modi...
में बचाया:
| मुख्य लेखकों: | , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4081642/ https://ncbi.nlm.nih.gov/pubmed/20053665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp588 |
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