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Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes

While high levels of Pkd1 expression are detected in tissues of patients with autosomal dominant polycystic kidney disease (ADPKD), it is unclear whether enhanced expression could be a pathogenetic mechanism for this systemic disorder. Three transgenic mouse lines were generated from a Pkd1-BAC modi...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Kurbegovic, Almira, Côté, Olivier, Couillard, Martin, Ward, Christopher J., Harris, Peter C., Trudel, Marie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081642/
https://ncbi.nlm.nih.gov/pubmed/20053665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp588
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