Cell-type specific interaction of endothelin and the nitric oxide system: pattern of prepro-ET-1 expression in kidneys of l-NAME treated prepro-ET-1 promoter-lacZ-transgenic mice

Nitric oxide (NO) and endothelin-1 (ET-1) are known to play a major role in renal and vascular pathophysiology and exhibit a close interaction with ET-1, stimulating NO production; NO in turn inhibits ET-1 expression. Our objectives were (1) to establish a novel transgenic mouse model facilitating E...

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Detalhes bibliográficos
Main Authors: Slowinski, Torsten, Kalk, Philipp, Christian, Maren, Schmager, Fred, Relle, Katharina, Godes, Michael, Funke-Kaiser, Heiko, Neumayer, Hans-H, Bauer, Christian, Theuring, Franz, Hocher, Berthold
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2007
Assuntos:
Renal and Endocrine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2170825/
https://ncbi.nlm.nih.gov/pubmed/17395629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.131201
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