Crystal structures of multidrug-resistant HIV-1 protease in complex with two potent anti-malarial compounds

類似資料

• P1 and P1' para-fluoro phenyl groups show enhanced binding and favorable predicted pharmacological properties: structure-based virtual screening of extended lopinavir analogs against multi-drug resistant HIV-1 protease
  著者:: Yedidi, Ravikiran S., 等
  出版事項: (2013)
• Contribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variants
  著者:: Yedidi, Ravikiran S., 等
  出版事項: (2011)
• Conserved Hydrogen Bonds and Water Molecules in MDR HIV-1 Protease Substrate Complexes
  著者:: Liu, Zhigang, 等
  出版事項: (2012)
• Design, synthesis and evaluation of a potent substrate analog inhibitor identified by scanning Ala/Phe mutagenesis, mimicking substrate co-evolution, against multidrug-resistant HIV-1 protease
  著者:: Yedidi, Ravikiran S., 等
  出版事項: (2013)
• Crystallographic study of multi-drug resistant HIV-1 protease Lopinavir complex: mechanism of drug recognition and resistance
  著者:: Liu, Zhigang, 等
  出版事項: (2013)