Proteomic Characterization of a Mouse Model of Familial Danish Dementia

A dominant mutation in the ITM2B/BRI2 gene causes familial Danish dementia (FDD) in humans. To model FDD in animal systems, a knock-in approach was recently implemented in mice expressing a wild-type and mutant allele, which bears the FDD-associated mutation. Since these FDD(KI) mice show behavioura...

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Detalhes bibliográficos
Main Authors: Vitale, Monica, Renzone, Giovanni, Matsuda, Shuji, Scaloni, Andrea, D'Adamio, Luciano, Zambrano, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350990/
https://ncbi.nlm.nih.gov/pubmed/22619496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/728178
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