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Proteomic Characterization of a Mouse Model of Familial Danish Dementia
A dominant mutation in the ITM2B/BRI2 gene causes familial Danish dementia (FDD) in humans. To model FDD in animal systems, a knock-in approach was recently implemented in mice expressing a wild-type and mutant allele, which bears the FDD-associated mutation. Since these FDDKI mice show behavioural...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Limited
2012-01-01
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| Colecção: | Journal of Biomedicine and Biotechnology |
| Acesso em linha: | http://dx.doi.org/10.1155/2012/728178 |
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