Development of Transgenic Cloned Pig Models of Skin Inflammation by DNA Transposon-Directed Ectopic Expression of Human β1 and α2 Integrin

Integrins constitute a superfamily of transmembrane signaling receptors that play pivotal roles in cutaneous homeostasis by modulating cell growth and differentiation as well as inflammatory responses in the skin. Subrabasal expression of integrins α2 and/or β1 entails hyperproliferation and aberran...

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Main Authors: Staunstrup, Nicklas Heine, Madsen, Johannes, Primo, Maria Nascimento, Li, Juan, Liu, Ying, Kragh, Peter M., Li, Rong, Schmidt, Mette, Purup, Stig, Dagnæs-Hansen, Frederik, Svensson, Lars, Petersen, Thomas K., Callesen, Henrik, Bolund, Lars, Mikkelsen, Jacob Giehm
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349713/
https://ncbi.nlm.nih.gov/pubmed/22590584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036658
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