Development of Transgenic Cloned Pig Models of Skin Inflammation by DNA Transposon-Directed Ectopic Expression of Human β1 and α2 Integrin

Integrins constitute a superfamily of transmembrane signaling receptors that play pivotal roles in cutaneous homeostasis by modulating cell growth and differentiation as well as inflammatory responses in the skin. Subrabasal expression of integrins α2 and/or β1 entails hyperproliferation and aberran...

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Main Authors: Staunstrup, Nicklas Heine, Madsen, Johannes, Primo, Maria Nascimento, Li, Juan, Liu, Ying, Kragh, Peter M., Li, Rong, Schmidt, Mette, Purup, Stig, Dagnæs-Hansen, Frederik, Svensson, Lars, Petersen, Thomas K., Callesen, Henrik, Bolund, Lars, Mikkelsen, Jacob Giehm
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349713/
https://ncbi.nlm.nih.gov/pubmed/22590584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036658
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