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The Impact of cHS4 Insulators on DNA Transposon Vector Mobilization and Silencing in Retinal Pigment Epithelium Cells

DNA transposons have become important vectors for efficient non-viral integration of transgenes into genomic DNA. The Sleeping Beauty (SB), piggyBac (PB), and Tol2 transposable elements have distinct biological properties and currently represent the most promising transposon systems for animal trans...

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Detalhes bibliográficos
Main Authors: Sharma, Nynne, Hollensen, Anne Kruse, Bak, Rasmus O., Staunstrup, Nicklas Heine, Schrøder, Lisbeth Dahl, Mikkelsen, Jacob Giehm
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482222/
https://ncbi.nlm.nih.gov/pubmed/23110238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048421
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