Managing MicroRNAs with Vector-Encoded Decoy-Type Inhibitors

A rapidly growing understanding of the complex circuitry of microRNA (miRNA)-mediated gene regulation is attracting attention to miRNAs as new drug targets. Targeted miRNA suppression is achieved in a sequence-specific manner by antisense RNA “decoy” molecules. Such synthetic miRNA inhibitors have r...

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Bibliographic Details
Main Authors: Bak, Rasmus O, Hollensen, Anne Kruse, Mikkelsen, Jacob Giehm
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2013
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734669/
https://ncbi.nlm.nih.gov/pubmed/23752312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.113
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