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Potent microRNA suppression by RNA Pol II-transcribed ‘Tough Decoy’ inhibitors

MicroRNAs (miRNAs) are key regulators of gene expression and modulators of diverse biological pathways. Analyses of miRNA function as well as therapeutic managing of miRNAs rely on cellular administration of miRNA inhibitors which may be achieved by the use of viral vehicles. This study explores the...

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Detalhes bibliográficos
Main Authors: Bak, Rasmus O., Hollensen, Anne Kruse, Primo, Maria Nascimento, Sørensen, Camilla Darum, Mikkelsen, Jacob Giehm
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543086/
https://ncbi.nlm.nih.gov/pubmed/23249752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.034850.112
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