Hybrid Lentivirus-transposon Vectors With a Random Integration Profile in Human Cells

Gene delivery by human immunodeficiency virus type 1 (HIV-1)-based lentiviral vectors (LVs) is efficient, but genomic integration of the viral DNA is strongly biased toward transcriptionally active loci resulting in an increased risk of insertional mutagenesis in gene therapy protocols. Nonviral Sle...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Staunstrup, Nicklas H, Moldt, Brian, Mátés, Lajos, Villesen, Palle, Jakobsen, Maria, Ivics, Zoltán, Izsvák, Zsuzsanna, Mikkelsen, Jacob Giehm
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2009
विषय:
Original Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835219/
https://ncbi.nlm.nih.gov/pubmed/19240688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.10
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