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Regulation of parkin and PINK1 by neddylation

Neddylation is a posttranslational modification that plays important roles in regulating protein structure and function by covalently conjugating NEDD8, an ubiquitin-like small molecule, to the substrate. Here, we report that Parkinson's disease (PD)-related parkin and PINK1 are NEDD8 conjugate...

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Autors principals: Choo, Yeun Su, Vogler, Georg, Wang, Danling, Kalvakuri, Sreehari, Iliuk, Anton, Tao, W. Andy, Bodmer, Rolf, Zhang, Zhuohua
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349425/
https://ncbi.nlm.nih.gov/pubmed/22388932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds070
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