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Regulation of parkin and PINK1 by neddylation
Neddylation is a posttranslational modification that plays important roles in regulating protein structure and function by covalently conjugating NEDD8, an ubiquitin-like small molecule, to the substrate. Here, we report that Parkinson's disease (PD)-related parkin and PINK1 are NEDD8 conjugate...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3349425/ https://ncbi.nlm.nih.gov/pubmed/22388932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds070 |
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